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Archive


Category Archive for "Service Blog"

Home BlogService Blog
1

Discovery of the Hepatitis C Virus —The 2020 Nobel Prize in Physiology or Medicine

Oct 6, 2020

By: Dr. Jie Jack Li, Vice President of Discovery Chemistry at ChemPartner   On October 5, 2020, the Nobel Assembly at the Karolinska Institute announced the Nobel Prize for Physiology or Medicine went to Harvey J. Alter, Michael Houghton, and Charles M. Rice “for their discovery of hepatitis C virus (HCV).” The worldwide incidence of […]

2

The Story of Dexamethasone

Jul 1, 2020

By: Dr. Jie Jack Li, Vice President of Discovery Chemistry at ChemPartner On June 16th, 2020, a team at Oxford University announced that their RECOVERY trials had revealed that a daily treatment of 6 mg of dexamethasone (Decadron, 1) lowered the fatality rate of ventilated COVID-19 patients by up to one third! This was a […]

3

How Is Remdesivir Made?

Jun 2, 2020

By: Dr. Jie Jack Li, Vice President of Discovery Chemistry at ChemPartner Gileadʹs antiviral drug remdesivir (Veklury, 1) was approved by the FDA on May 1st for emergency use against coronavirus disease-2019 (COVID-19) after just a one-day review. Now the onerous task falls upon Gilead to make enough of the drug to supply doctors and […]

4

Genesis of Remdesivir

May 27, 2020

By: Dr. Jie Jack Li, Vice President of Discovery Chemistry at ChemPartner Gileadʹs antiviral drug remdesivir (Veklury) was approved by the FDA on May 1, 2020 for emergency use in coronavirus disease-2019 (COVID-19) patients after a one-day review. It took the Japanese government much longer to give the nod, seven days, before granting its regulatory […]

5

How Does Remdesivir Work?

May 2, 2020

By: Dr. Jie Jack Li, Vice President of Discovery Chemistry at ChemPartner Gileadʹs antiviral drug remdesivir has been catapulted to the limelight as the only FDA-approved treatment of coronavirus Covid-19 for emergency use thus far. On April 29, 2020, preliminary clinical trials indicated that the drug has shown some efficacy. While mortality rate for patients […]

6

Meeting Chiral Separation Efficiency Needs in Pharmaceutical Discovery with Supercritical Fluid Chromatography

Sep 19, 2019

By: Dr. Manny Ventura, Director and Global Head of Analytical Chemistry at ChemPartner Supercritical fluid chromatography (SFC) is now a well-established tool incorporated into the small molecule drug development strategy for organizations of all types and sizes. Its imprint is almost surely on the history of development of any new advanced chiral drug candidate. Big […]

7

Innovations in Lead Generation Through Fragment-Based Screening

Apr 18, 2019

By: Dr. Kevin Greenman, Principal Scientist at ChemPartner When it comes to finding new chemical matter to engage biological targets, fragment-based screening (FBS) offers a number of advantages over traditional high-throughput screening (HTS). The success of this approach has resulted in a growing list of molecules advancing through clinical trials. From the perspective of a […]

8

ANTIBODY DISCOVERY THROUGH B CELL CLONING

Jan 31, 2019

By: Dr. Shireen Khan, Senior Director of Biologics at ChemPartner Through our partnership with single cell technology company Berkeley Lights, Inc., ChemPartner offers the innovative Optofluidic based Beacon® platform at our South San Francisco lab. The nano chip technology of the  Beacon® platform enables  functional characterization of  antibodies secreted from single B cells. The Berkeley […]

Latest News

ChemPartner Makes Additional Investments in Biologics from Research to Manufacturing Capabilities

06/11/2020

Shanghai, China (June 9, 2020) – Shanghai ChemPartner...

ChemPartner Assists the Mount Sinai Health System in Producing Reagent for COVID-19 Research

05/12/2020

Shanghai, China (May 12, 2020) – Shanghai ChemPartner...

ChemPartner and the Gladstone Institutes Announce COVID-19 Research Collaboration

04/17/2020

SAN FRANCISCO, Calif. and SHANGHAI, China. (April 15, 2020)...

ChemPartner Introduces New State-of-the-Art Global Operation Center in Shanghai

04/02/2020

Shanghai, China (March 17, 2020) – Shanghai ChemPartner...

Dr. Jie Jack Li joins Shanghai ChemPartner as a Vice President of Discovery Chemistry

12/18/2019

Shanghai, China (December 17, 2019) – Shanghai ChemPartner...

Shanghai ChemPartner was awarded “TOP 10 CMOs in 2019”

Shanghai ChemPartner was awarded “TOP 10 CMOs in 2019”

07/19/2019

Contract manufacturers play a significant role when it comes...

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