Library Chemistry
We can design small property, target class focused libraries or larger DOS type libraries. We work closely with our computational and structural groups on design. Our designs are guided by structure-based drug design when crystal structures are available, and our computational group for property-based metrics. We can deliver compounds in a variety of formats or deliver them ready for screening to our in vitro biology group or in vitro DMPK group.
As fits with todays techniques in medicinal chemistry libraries are most often executed in SAR enhancing sets of 50 -200 compounds, however ChemPArtner has experience and in delivering both small and large libraries. This can either be a stand alone request from clients or can be accessed as part of a broader medicinal chemistry lead optimization effort where a small library can make sense to rapidly investigate SAR.
- Service Overview
- Discovery Chemistry
- Biology & Pharmacology
- Biologics Discovery
- DMPK / Exploratory Toxicology
- Biologics CMC
- Small Molecule CMC