Apart from antibody humanization and antibody discovery from phage display, ChemPartner’s antibody engineering department also offers sequence optimization and affinity maturation services. We provide customized affinity maturation strategies [random mutagenesis...
ChemPartner’s proprietary fully human naïve phage library with diversity ~10^11. Efficient library selection and screening with high-throughput robotics. All V-genes were amplified with high fidelity from diverse healthy donors. Stringent cloning procedures ensure a...
Specific Pathogen Free (SPF) animals and multiple species/strains such as SJL mice and SD rats New Zealand White rabbit are available for immune phage library approach Animal strains with superior immune response to highly conserved and multi-transmembrane protein...
Immunogen and Antigen Preparation Recombinant protein production and cell line development Peptide and compound design and synthesis DNA In vivo transfection Binding Assays and Bioassays Well-established assays Assay development and optimization for hybridoma...
ChemPartner has a top-tier antibody drug conjugate (ADC) team spanning multiple areas, such as antibody development, medicinal chemistry, DMPK, and in vitro/in vivo pharmacology. In addition to individual function service packages, ChemPartner also provides all-in-one...
ChemPartner’s phage display and high throughput screening group offers streamlined services for fully human therapeutic antibody discovery and optimization, also providing coherent protein engineering, immune library construction, and screening for general biologics...
ChemPartner’s antibody engineering team performs antibody sequencing and chimeric antibody generation routinely. Supported by an elite protein structure team in modeling area, we are able to do hotspot analysis and removal, world-class humanization design with...
ChemPartner’s hybridoma group provides premium monoclonal antibody services with our advanced hybridoma platform, which has been validated by more than 100 integrated therapeutic projects and a large number of reagent mAb projects. A number of key technologies are...
ChemPartner expanded our antibody discovery service offering to include B cell cloning in January 2019. The Beacon® platform is capable of screening thousands of plasma B cells from immunized animals, which speeds up a traditionally time-consuming hybridoma process....
ChemPartner’s biologics analytical team offer full range of biologics analytical, biophysical capabilities supporting discovery and development of preclinical antibodies/therapeutic proteins. Parameter Method Primary Sequence Composition Amino acid analysis (AAA)...
