Immunology and Inflammation Archives | ChemPartner

Luminex

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Luminex

by Sarah Stapleton | Mar 5, 2021

Customized commercial kits Multiplexing with up to 80 analytes per well Validated Analytes Pool 253 Human targets 108 Mouse targets 104 Monkey targets 35 Rat targets QC Criterial Inner and inter-plate standard signal CV tracking Luminex Reader List 2D System Bio-Plex...

Luminex

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Multi-color Flow Cytometry

by Sarah Stapleton | Mar 5, 2021

Multi-channel flow cytometer Customized panel design 96/384-well plate auto-sampler High-throughput screening Method development service Thermo Attune NxT Gentle MACS Dissociator Beckman...

Ex Vivo Analysis Platforms

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Ex Vivo Analysis Platforms

by cstolzerhy | Mar 5, 2021

Multi-color Flow Cytometry Luminex Quantigene ELISPOT

Ex Vivo Analysis Platforms

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Systemic inflammation in mice (Con A)

by Sarah Stapleton | Mar 5, 2021

Con-A Induced Systemic Inflammation in Mice Animal: BALB/c mice, female, 9-11 weeks Modeling: ConA (15 MPK) injection through tail veins Reference drug: Dexamethasone Readouts: Body weight, liver/spleen weight, ALT and AST level in serum, inflammatory cytokines...

Ex Vivo Analysis Platforms

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IMQ induced psoriasis in mice

by Sarah Stapleton | Mar 5, 2021

Animal: BALB/c mice, female, 7.5 weeks Modeling: IMQ painted on shaved back skin daily Reference Drug: Tofacitinib, p.o., BID Readouts: Body weight, PASI score, skin thickness, pathology PASI Score Criterial: Erythema, scale, and thickness 0: no; 1: mild; 2: moderate;...

Ex Vivo Analysis Platforms

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Adjuvant induced arthritis in rats (AIA)

by Sarah Stapleton | Mar 5, 2021

Animal: Lewis rat, female, 180-200g Immunizations: CFA Readouts: body weight, joint swelling, clinical score, pathology, x-ray

Ex Vivo Analysis Platforms

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Autoimmune Disease and Inflammation In Vivo Models

by cstolzerhy | Mar 5, 2021

Respiratory Disease OVA-induced asthma in mice HDM-induced asthma in mice Bleomycin-induced lung fibrosis in mice Rheumatoid Arthritis Collagen-induced arthritis in rats (CIA) Adjuvant-induced arthritis in rats (AIA) Multiple Sclerosis (MS) MOG-induced EAE in mice...

Ex Vivo Analysis Platforms

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Th Subsets Differentiation (Th1/2/17/Treg) Assays

by Sarah Stapleton | Mar 5, 2021

Primary T Cell Differentiation Assay Species: human and mouse Type: Th1, Th2, Th17, Treg Cell Source: Naïve CD4+ T cell from hPBMC or mouse spleen tissue Th1: IFN-g+ Cells% by FACS Th17: IL-17a Conc. by ELISA Treg: CD25+Foxp3+ Cells% by FACS...

Ex Vivo Analysis Platforms

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T Cells (Total, CD4+, CD8+) Activation and Proliferation Assays

by Sarah Stapleton | Mar 5, 2021

T Cell Activation Assay Customized Assay Format Cell Source: PBMC, CD3+ T, CD4+ T, CD8+ T Stimulation: TA in the presence or absence of anti-CD3/28, PHA, PMA, SEB Readout: Cell proliferation (CTG/FACS), cytokine release (ELISA/Luminex) ...

Ex Vivo Analysis Platforms

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Mixed Lymphocyte Reaction (MLR) Assay

by Sarah Stapleton | Mar 5, 2021

The MLR assay is considered the ‘gold standard’ T cell functional assay for the test of T cell immune checkpoint inhibitors Dendritic cells co-cultured with allogeneic CD3+ T cells Readouts: IFN-γ and IL-2 production Suitable to test both antibodies and small...

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