Behavioral Pharmacology

Behavioral Pharmacology

Neurodegeneration Alzheimer’s Disease – 5x Familial AD Transgenic Mice Biomarkers, pathology, EEG, behavioral tests, LTP in brain slice Parkinson’s Disease – 6-OHDA Rats Apomorphine or L-DOPA challenged rotation L-DOPA induced dyskinesia in 6-OHDA rats...
Behavioral Pharmacology

In Vitro Electrophysiology and Ex Vivo Assays

Ion Channel Targets Voltage-gated Ion Channels (K+) hERG (Na+) Nav 1.5, Nav 1.7, Nav 1.1 Ligand-gated Ion Channels TRP Family (TRPV1, V3, C6) P2X Family (P2X3, 4, 7) GABAaR (1α, 2β, γ2) GluR (AMPA, NMDA) Family   In Vitro and Ex Vivo CNS Biomarkers High content...