Behavioral Pharmacology

Behavioral Pharmacology

Neurodegeneration Alzheimer’s Disease – 5x Familial AD Transgenic Mice Biomarkers, pathology, EEG, behavioral tests, LTP in brain slice Parkinson’s Disease – 6-OHDA Rats Apomorphine or L-DOPA challenged rotation L-DOPA induced dyskinesia in 6-OHDA rats...
Behavioral Pharmacology

In Vitro Electrophysiology and Ex Vivo Assays

Ion Channel Targets Voltage-gated Ion Channels (K+) hERG (Na+) Nav 1.5, Nav 1.7, Nav 1.1 Ligand-gated Ion Channels TRP Family (TRPV1, V3, C6) P2X Family (P2X3, 4, 7) GABAaR (1α, 2β, γ2) GluR (AMPA, NMDA) Family In Vitro and Ex Vivo CNS Biomarkers High content image...