Oncology Archives | ChemPartner

Case Studies in the Syngeneic Model

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Case Studies in the Syngeneic Model

by Sarah Stapleton | Mar 4, 2021

Efficacy Test in CT2.WT Model Tumor Growth Survival Evaluation (Endpoint: TV > 2000mm3 Mice under combination therapy exhibited survival benefit Efficacy Test in 4T1 Resection Model Tumors were resected on D13; Half mice to observe survival;...

Case Studies in the Syngeneic Model

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Case Studies in PDXs

by Sarah Stapleton | Mar 4, 2021

Mouse Clinical Trial in PDXs Objective: to evaluate drug efficacy across 17 colorectal PDXs Pre-defined Clinical Endpoints Tumor Progression A tumor volume change >73% by the end of treatement Tumor Stasis A tumor volume change between -66% and 73% by the end of...

Case Studies in the Syngeneic Model

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Model Generation Study in CDXs

by Sarah Stapleton | Mar 4, 2021

Tumor Volume Change of NCl-H661 subQ Model Total Flux in U87MG-Luc2 Orthotopic Model

Case Studies in the Syngeneic Model

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Case Studies in the Syngeneic Model" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Case Studies in CDXs

by Sarah Stapleton | Mar 4, 2021

Efficacy Study in CDXs Tumor Growth Inhibition in MV-4-11 Survival Rate in A375 Brain Inoculation Tumor Growth Inhibition in Hep3B 2.1-7 Efficacy and Biomarker Assessment in CDXs Cancer Discovery. 2018 Jul;8(7):836-849 Cell line derived allograft and xenograft models...