MOA Study

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In addition to assay development and compound profiling, ChemPartner’s in vitro biology team has the robust expertise related to the enzymology necessary to conduct in-depth research on the mechanism of action (MoA) for compounds, including reversibility studies, competition studies, and kinetic analysis (Ki, kon, koff, kinact determination).

 

Kinetic Analysis

Time-dependent Inhibition

 

Slow-off vs Irreversible Cmpds

 

Ki, kinact Determination

 

Modality of Inhibition

Competitive

 

Non-Competitive

 

Un-Competitive

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