In Vitro Electrophysiology and Ex Vivo Assays

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Ion Channel Targets

  • Voltage-gated Ion Channels
    • (K+) hERG
    • (Na+) Nav 1.5, Nav 1.7, Nav 1.1
  • Ligand-gated Ion Channels
    • TRP Family (TRPV1, V3, C6)
    • P2X Family (P2X3, 4, 7)
    • GABAaR (1α, 2β, γ2)
    • GluR (AMPA, NMDA) Family

 

In Vitro and Ex Vivo CNS Biomarkers

  • High content image analysis system for neurites
  • ELISA assays of neurofilament light protein/progranulin for neuronal degeration
  • Neural histology with confocal microscope, PSD95/SV2A, golgi staining
  • AAV carried gene expression in cochlea and ex plant

 

Electrophysiology Platforms

  • Transient/stable cell lines
  • Primary cultural of DRG, hippocampal, cortical neurons
  • Ex vivo brain slices for
    • LTP/LTD or neuronal excitability in:
      • Hippocampus (CA1, CA3, DG)
      • Frontal cortex
      • Cortex-striatum
      • N Accumbens
      • Amygdala
      • Interpeduncular nucleus
  • Automated Qpatch-48
  • Manual patch clamp EPC10 USB, 700B
  • Multi-electrode array MED64 system

 

Headquarters

1F & 3F, Block A
2829 JinKe Road
Zhangjiang Hi-Tech Park
PuDong New Area
Shanghai China, 201203

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China: +86 21 5132 0088
US: +1 650 419 9974
Europe: +45 4586 9000
Japan: +81 03 5403 6975

contact@chempartner.com