Fully Human Therapeutic mAb Discovery

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  • ChemPartner’s proprietary fully human naïve phage library with diversity ~10^11. Efficient library selection and screening with high-throughput robotics.
  • All V-genes were amplified with high fidelity from diverse healthy donors. Stringent cloning procedures ensure a high percentage of functional clones in the library.
  • Independent VH, VL libraries maximize V-gene recovery and facilitate subsequent affinity maturation with chain shuffling
  • All V-gene families are individually cloned and assembled, maximizing library diversity and reducing gene bias due to PCR cloning.
  • First major naïve antibody library built with predefined V-gene composition to match the human immune repertoire

 

  

 

 

 

 

CP naïve library V-gene composition matches the natural repertoire.

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1F & 3F, Block A
2829 JinKe Road
Zhangjiang Hi-Tech Park
PuDong New Area
Shanghai China, 201203

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China: +86 21 5132 0088
US: +1 650 419 9974
Europe: +45 4586 9000
Japan: +81 03 5403 6975

contact@chempartner.com