Carbohydrate Chemistry
Carbohydrate chemistry for glycoscience programs that most synthesis groups turn down. We handle protecting-group strategy, stereoselective glycosylation and oligosaccharide assembly, delivering defined glycans and glycoconjugates with the analytical data to prove structure and anomeric purity.
OVERVIEW
Everything a sponsor evaluating an outsourced biologics CMC partner needs to know — from capacity to compliance.
Carbohydrate chemistry has been a specialized research area at ChemPartner since our founding. We have extensive expertise and solid experience in the synthesis of complex carbohydrates and their conjugates with a proven track record over the last twenty years.
Carbohydrate chemistry is highly challenging due to polarity, chemical complexity, complicated stereochemistry, and difficult glycosylation. The lack of a chromophore makes the analysis and purification more difficult than that of small molecules. In many cases, complex protection strategies are often needed in carbohydrate chemistry.
With over 20 years of experience in carbohydrate chemistry and a specialized team of chemists, we synthesize:
- Modified monosaccharide building blocks
- Glucuronide metabolites of drug candidates
- Conjugates of peptidosaccharides, liposaccharides, and nucleotide-saccharides
- Polysaccharides and oligosaccharides
