Translational insights from target to disease model

ChemPartner integrates molecular biology, assays, biomarkers, and disease models into a connected translational workflow that helps programs move from biological hypothesis to decision-ready data.

Start with the critical decision your program needs to make next.

Choose your starting point

Molecular Biology

Target validation, engineered cell systems, CRISPR, siRNA, and shRNA capabilities.

Biochemistry

Binding, enzymology, receptor activation, phosphorylation, and protein interaction assays.

Cell-Based Assays

Target engagement, signaling, proliferation, ADC, TPD, and nucleic acid workflows.

Functional Assays

Biological activity, immune activation, GPCR, ion channel, and behavioral readouts.

Biomarker Analysis

Immunophenotyping, cytokine profiling, receptor occupancy, pSTAT, and translational sample analysis.

Disease Models

In vivo efficacy, PK/PD evaluation, histopathology, and ex vivo pharmacology endpoints.

Immunology Assays

Cell-based and functional assays to assess immune-cell activation, cytokine response, target engagement, and immune-modulating activity.

Oncology Assays

Cancer-relevant cellular and functional assays to evaluate target biology, tumor-cell response, mechanism of action, and treatment combinations.

Neuroscience Assays

Specialized in vitro and ex vivo assays to assess neurobiology, neuronal function, target engagement, and CNS-relevant pharmacology.

How programs connect

Programs advance from early biological validation to translational evidence through the right combination of assays, biomarkers, and disease models.

Validate the Target

Establish biological relevance and mechanism through molecular biology and biochemistry studies.

Build the Assay

Measure potency, signaling, and biological activity in relevant cellular and functional systems.

Add Biomarkers

Link experimental findings to translational readouts across blood, tissue, PBMC, tumor, and related samples.

Select Disease Models

Extend insights into in vivo efficacy, PK/PD relationships, and disease-relevant outcomes.

Translational Science by therapeutic area

When programs become disease-focused, dedicated platform teams connect assays, biomarkers, and model systems within the appropriate biological context.

Immunology

Integrate immune-cell assays, biomarker strategies, and disease models for immunology and inflammation programs.

Oncology

Connect target validation, cancer biology assays, biomarkers, and tumor models for oncology research.

Neuroscience

Access CNS screening, electrophysiology, biomarkers, and neuroscience models across in vitro and in vivo platforms.

Metabolic Diseases

Integrate disease-relevant models, metabolic phenotyping, biomarker analysis, and PK/PD studies for metabolic disease programs.

Cardiovascular

Support cardiovascular discovery with translational assays, disease models, biomarker strategies, and functional pharmacology endpoints.

Infectious Diseases

Advance anti-infective programs with pathogen-focused assays, host-response models, microbiology expertise, and translational pharmacology support.

Not sure where to start?

Share your target, modality, species, and key decision point, and our team can help identify the most relevant assay, biomarker, and disease model strategy.