Integrated discovery chemistry, from target to IND

ChemPartner capabilities for integrated medicinal chemistry, synthetic chemistry, AIDD, analytical support, and new-modality discovery — connected in one design-make-test-analyze workflow.

Integrated chemistry, from hit identification to IND-enabling support

ChemPartner provides integrated discovery chemistry CRO services for biotech and pharma teams — spanning target and hit identification, hit-to-lead, lead optimization, preclinical candidate selection, and IND-enabling support. Medicinal chemistry leadership, synthetic execution, AI-enabled design, biology, DMPK, pharmacology, and early development connect in one practical design–make–test–analyze workflow.

Delivered from dedicated chemistry sites in Chengdu and Lingang — supporting programs from emerging biotech through all Top-20 multinational pharmaceutical companies.

medicinal, synthetic and analytical chemists
700+
OPERATING FUME HOODS
1,000+
ACTIVE CLIENTS SERVED
200+
reactions per FTE per week
12+

One design–make–test–analyze workflow, hit to IND

01
Hit ID
Assay development & hit finding
02
Hit-to-lead
Series triage & selection
03
Lead optimization
Multi-parameter SAR
04
PCC generation
Preclinical candidate
05
CMC development
Scale-up & process
06
IND-ready
Data package for filing

Core capabilities across the chemistry workflow

Scale

700+ chemistry professionals, 1,000+ fume hoods, chemistry sites supporting discovery and scale-up.

Discovery workflow

Hit ID, hit-to-lead, lead optimization, PCC generation, CMC development, and IND-ready packages.

AIDD and CADD

Virtual screening, de novo design, scaffold hopping, ADMET prediction, FEP, and retrosynthesis.

New modalities

PROTACs, ADC/XDC linker-payloads, peptides, oligonucleotides, conjugates, and related chemistry platforms.

Analytics

LCMS, NMR, SFC, prep-HPLC, chiral separation, impurity isolation, HRMS, and full characterization.

Engagement

FTE, FFS, blended teams, integrated programs, milestone-based projects, and long-term partnerships.

Purpose-built platforms for new modalities

Beyond small molecules, ChemPartner runs dedicated modality platforms — each with specialist chemists and documented throughput — for PROTACs and degraders, ADC/XDC linker-payloads, peptides, and oligonucleotides.

PROTAC & Degrader Chemistry

100+ PROTAC chemists delivering 1,000+ compounds per year.

ADC/XDC Linker-Payload Chemistry

Develop tailored linkers and payloads to support stable, effective antibody and next-generation conjugate programs. 

Peptide Chemistry

Advance peptide therapeutics with integrated design, synthesis, modification, and optimization capabilities.

Oligonucleotide Chemistry

Accelerate oligonucleotide programs with specialized synthesis, modification, conjugation, and analytical expertise.

Molecular Glue Discovery

Design and optimize molecular glues that enable targeted protein degradation through novel proteinprotein interactions. 

Before you scope a program

What discovery stages does ChemPartner support?

ChemPartner supports assay development, hit finding, hit-to-lead, lead optimization, PCC generation, CMC development, DMPK, pharmacology, toxicology, and IND-ready data packages.

Yes. ChemPartner supports both traditional small-molecule discovery and specialized new-modality programs, including medicinal and synthetic chemistry, PROTACs and degraders, ADC/XDC linker-payloads, peptides, oligonucleotides, and related conjugation platforms.

AIDD is used for virtual screening, de novo molecular generation, scaffold hopping, ADMET prediction, structure-based design, FEP calculations, retrosynthetic analysis, and multi-objective optimization.

Capabilities include LCMS, NMR, prep-HPLC, SFC, chiral analysis and purification, impurity isolation, HRMS, GC/MS, ICP-OES, IR, UV, DSC, TGA, and full structure characterization.

ChemPartner offers dedicated FTE teams, fee-for-service work, function-based or blended teams, and integrated programs that combine chemistry, biology, DMPK, pharmacology, and early toxicology.

Start a discovery chemistry engagement

Connect

Discuss a discovery chemistry program

Connect with ChemPartner to scope target-, hit-, lead-, or PCC-stage chemistry support.

Explore

Build an integrated team

Explore FTE, fee-for-service, blended, or integrated chemistry–biology–DMPK engagement models.

Review

Explore a modality platform

Review PROTAC, ADC linker-payload, peptide, oligonucleotide, and analytical capabilities.

START YOUR JOURNEY
Phase
Modality
Therapeutic Area