Biomolecular Interaction Analysis
Protein-protein interaction analysis with the kinetics behind the number. SPR, BLI and calorimetry deliver on-rates, off-rates and affinity for antibody, small molecule and complex systems — measured under conditions that reflect the biology rather than the convenience of the instrument.
OVERVIEW
Kinetics | Affinity | Thermodynamics
How fast, strong & why… Is the binding of a lead antibody or compound?
Specificity
How specific & selective… Is this drug binding to its receptor?
Concentration
How much… Is the biologically active component in a production batch?
Various Types of Interaction Analysis
- Antibody-antigen or receptor-ligand interaction characterization: affinity, kinetics
- High-throughput compound library screening
- KD measurement of compounds binding to target proteins
- scFv or antibodies screening and ranking
- Identifying the logical sequence of binding events for multimolecular complexes
- Epitope binning, isotyping and cross-reactivity test of antibodies.
Biacore Models
- Biacore X100
- Biacore T200
- Biacore 8K
ForteBio Model
- Octet Red 384
