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In Vitro Pharmacology

In vitro pharmacology services spanning biochemical, cellular and phenotypic readouts. Target classes from kinases and GPCRs to epigenetic and degradation targets, run by teams that also build the custom assays when the catalogue format will not answer the question.

OVERVIEW

Custom assays for kinases, GPCRs, and PROTACs along with MOA assays and blood cell screeing provide robust data for lead optimization.

Explore Our Capabilities:

Immune Cell Assays

- Primary Immune Cell Assays

- Th Subsets Differentiation Assays

- Mixed Lymphocyte Reaction (MLR) Assay

- T Cells Total CD4/CD8 Activation and Proliferation Assays

- Whole Blood/PBMC Stimulation and Cytokine Release Assay

Functional and Cell Assays

- Cell Functional Assays

- Cell Signaling Assays

- Functional Assay Panels

- In Vitro Electrophysiology and Ex Vivo Assays

- Cancer Cell Line Panel Screen

Target-Specific Assays

- Radiometric

- Ubiquitin/PROTAC

- Kinases

- Epigenetics

- KRAS

- COVID-19

- Antibody Target Specific Assays

- Small Molecule Target Specific Assays

Custom Development and Safety

- MOA Study

- Pharmacology Safety Panel

- GPCR/NR/Ion Channel/Transporter

- Customized Assay Development

- Comprehensive In Vitro Proarrhythmia Assay (CiPA)