Autoimmune Disease and Inflammation Models
Preclinical autoimmune disease and inflammation models across six indication areas — rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, respiratory disease and systemic inflammation. Established protocols including CIA, AIA, EAE, IMQ-induced psoriasis and DSS colitis, with readouts matched to your mechanism.
Respiratory Disease
- OVA-induced asthma in mice
- HDM-induced asthma in mice
- Bleomycin-induced lung fibrosis in mice
Rheumatoid Arthritis
- Collagen-induced arthritis in rats (CIA)
- Adjuvant-induced arthritis in rats (AIA)
Multiple Sclerosis (MS)
- MOG-induced EAE in mice
- PLP-induced EAE in mice
Skin-related Disease
- IMQ-induced psoriasis in mice
- IL-23-induced hyperplasia in mice
- Passive cutaneous anaphylaxis in mice (PCA)
- DNFB/Oxa-induced delayed type hypersensitivity in mice (DTH)
Inflammatory Bowel Disease (IBD)
- DSS-induced IBD in mice(acute)
Systemic Inflammation or Other:
- LPS-induced cytokine release in mice
- Systemic inflammation in mice (Con A)
- Air pouch in rats
