TIL Subpopulation Screening in Syngeneic Models

TIL subpopulation analysis in syngeneic tumor models. We profile tumor-infiltrating lymphocyte populations alongside efficacy readouts, showing how treatment reshapes the immune compartment inside the tumor rather than only what happened to its volume.

TIL baselines were profiled in top ten popular tumor models:

  • CT26.WT
  • MC-38
  • 4T1
  • B16-F10
  • EL4
  • EMT-6
  • Hepa1-6
  • A20
  • LLC1
  • Renca

Data expressed are average values of 3 tumors of 500-1000 mm3 for each model. 

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